DIFFERENTIAL DIAGNOSIS OF STERILE AND I NFECTED PANCREONECROSIS

  • V. V. Boyko
  • V. M. Lykhman
  • A. O. Merkulov
  • D. O. Myroshnychenko
  • S. V. Tkach
  • N. V. Batsman
  • E. O. Bilodid
  • A. V. Moskalenko
Keywords: pancreatic necrosis, differential diagnosis, clinical and laboratory indicators.

Abstract

Summary. Introduction. The search for objective methods for diagnosing the form and severity of acute pancreatitis, accurate prediction and timely prevention of infectious complications in this surgical pathology is of great practical importance for modern medicine.

Materials and methods. According to clinical, morphological and bacteriological data, groups of patients were selected. The first group included 33 patients with sterile pancreatic necrosis (SP), the second group consisted of 29 patients with infected pancreatic necrosis (IP).

Results and discussion. The program of differential diagnosis of sterile and infected pancreatic necrosis with calculation of the index of differential diagnosis (IDD) for each clinical-laboratory and instrumental indicator used in this system is developed. The development and evaluation of diagnostic possibilities of the method of verification of purulent-septic complications of acute pancreatitis and the transition of a sterile form of pancreatic necrosis to an infected one was carried out.

Conclusions. The use of the developed method of diagnosis of sterile and infected pancreatic necrosis with the calculation of the index of differential diagnosis allowed in 93% of cases to distinguish sterile pancreatic necrosis from infected and timely determine the scope and tactics of treatment.

References

1. Noskov IG. Metody lecheniya postnekroticheskih kist podzheludochnoj zhelezy: sovremennyj vzglyad na problemu (obzor literatury). Acta Biomedica Scientifica.2017;5:155-62. [In Rus.].
2. Babaev DA. Inficirovannyj neotgranichennyj pankreonekroz i ego pozdnie postnekroticheskie, septicheskie oslozhneniya (osobennosti kliniki, diagnostiki, operativnogo lecheniya) [dissertaciya].M. 2017, 26 s. [In Rus.].
3. Ostrovskij VK, i dr. Pankreonekroz – osnovnaya prichina letal’nosti pri peritonite u umershih vne stacionara [Elektronnyj resurs]. Sovremennye problemy nauki i obrazovaniya. 2015;1(1):6 s. [In Rus.].
4. Aleksashina DS. Programma differencial’noj diagnostiki asepticheskogo i inficirovannogo pankreonekroza [dissertaciya]. Volgograd, 2018, 29 s. [In Rus.].
5. Krasil’nikov DM, i dr. Hirurgicheskaya taktika pri pankreonekroze i ego oslozhneniyah. Teoreticheskaya i klinicheskaya medicina. 2016; T.97, 6:898-903. [In Rus.].
6. Kim DA. Obosnovanie hirurgicheskoj taktiki pri ostrom tyazhelom nekrotiziruyushchem pankreatite [dissertaciya]. Novosibirsk, 2018. 22 s. [In Rus.].
7. Plasma cytokines can help to identify the development of severe acute pancreatitis on admission / L. H. Deng, [et al.] // Medicine (Baltimore). – 2017. – Vol. 96, № 28 – P. 7312.
8. Rahimov RR. Sovershenstvovanie diagnosticheskoj i lechebnoj taktiki pri steril’nom i inficirovannom pankreonekroze [dissertaciya].Ufa, 2018, 21 s. [In Rus.].
9. Bressan AK, Ball CG. Intra-abdominal hypertension and abdominal compartment syndrome in acute pancreatitis, hepato-pancreato-biliary operations and liver transplantation. Anaesthesiology Intensive Therapy. 2017;49(2):159- 66. [In Rus.].
10. Liu J, et al. How to predict the severity of acute pancreatitis? An ongoing debate. Turk. J. Gastroenterol.2017;28(3): 230.
Published
2021-03-20
How to Cite
Boyko, V. V., Lykhman, V. M., Merkulov, A. O., Myroshnychenko, D. O., Tkach, S. V., Batsman, N. V., Bilodid, E. O., & Moskalenko, A. V. (2021). DIFFERENTIAL DIAGNOSIS OF STERILE AND I NFECTED PANCREONECROSIS. Kharkiv Surgical School, (1), 31-35. https://doi.org/10.37699/2308-7005.1.2021.06
Section
QUESTIONS OF SURGERY OF PANCREATOBILIARY SYSTEM

Most read articles by the same author(s)

<< < 1 2 3 4 5 > >>