TY - JOUR AU - V. V. Boiko AU - T. A. Kurbanov AU - O. V. Kravtsov AU - Yu. I. Isaev AU - E. A. Kravtsova PY - 2020/03/12 Y2 - 2024/03/29 TI - CLINICAL DYNAMICS OF TISSUE CHANGES IN THE FORMATION OF COMPARTMENT SYNDROME IN BURNS JF - Kharkiv Surgical School JA - Khark. Surg. Sch. VL - 0 IS - 3 SE - QUESTIONS OF BURN DISEASE DO - 10.37699/2308-7005.3.2020.09 UR - https://surgical-school.com.ua/index.php/journal/article/view/141 AB - Summary. Compartment syndrome — local hypertensive-ischemic syndrome - a formidable complication of traumatic tissue damage, the basis of which is the increase in intrafascial pressure of muscle masses above 20 mm. The treatment of this dangerous condition is carried out by emergency surgery to decompress tissues.The aim of the study was to study in an experiment the clinical and morphological development of the compartment syndrome for burns and to evaluate the effectiveness of necrotomy operations and impregnation of affected tissues with ozonized physiological saline.Materials and methods. The experiment was carried out on 18 rats of the WAG line, weighing 190-210 g. The study material was skin with adjacent soft tissues of the thigh area. To simulate experimental deep burns, we used a device developed by us for the formation of burns, standard in depth and area of the lesion. After the burn was formed, interstitial pressure was measured.Research results and discussion. The dynamics of macroscopic observations of the wound process and x-ray studies reflect their correspondence to the severity of thermal injury and the positive impact of the proposed therapeutic measures.Сonclusions.The development of the compartment syndrome with circular and subcircular limb burns and electric burns is a formidable complication, leading to a sharp deterioration in thermal injury and requires immediate surgical intervention.The critical point of the level of interstitial pressure should be considered 20 mm, the increase is an absolute indicator for the operation.The effectiveness of necrotomy can be improved by the use of a number of medications, in particular local infiltration with ozonized saline. ER -