PECULIARITIES OF BACTERIAL KERATITIS IN PATIENTS WITH DIABETES MELLITUS DEPENDING ON THE SEVERETY OF DIABETIC POLINEUROPATHY
Summery. The dependence of the peculiarities of bacterial keratitis on the severity of DPN was proven with the help of 15 patients with type 1 diabetes mellitus. During all periods of observation, the severity of conjunctival hyperemia, the size of erosion and the threshold of corneal sensitivity at the stage of severe complications exceeded the corresponding indicators of patients with asymptomatic DPN. Normalization of conjunctival color in all patients with severe complications occurred at 8 days, and reepithelialization of the cornea 4 days later than in asymptomatic DPN. On the last 22nd day of observation, the corneal opacification of the peripheral localization remained in 33.3% of patients (2 patients) with the stage of severe complications, whereas in all patients with asymptomatic DPN the cornea was already transparent on the 14th day of observation. The threshold of corneal sensitivity at 22nd day in patients with severe complications was 35.3% higher than with asymptomatic DPN (p <0.05). So, patients with severe complications DPN with bacterial keratitis show a more pronounced violation of corneal innervation, which manifests by decrease of its sensitivity, and leads to prolongation of the duration of the disease.
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