NUMBER OF COMMON BILE DUCT STONES WITHOUT CHOLANGITIS CORRELATES WITH BACTERIOLOGIC ASSESSMENT OF BILE

  • I. N. Mamontov
Keywords: bile obstruction, common bile duct stones, bacteriobilia

Abstract

Abstract. Aim: to determine the factors influencing on bacteribilia in patients with benign obstruction of the extrahepatic biliary tract (BOEBT).

Materials and Methods. A study of 30 cases of BOEBT with bacteriologic bile assessment was performed. A comparison of the incidence of different factors in patients with or without bacteriobilia was done.

Results. Positive bile culture was in 22 (73.3%) patients. The most common were E. coli and Klebsiella (68.2%). There was no difference (p<0.05) in sex, age, bilirubin level, gallbladder condition, common bile duct size, major duodenal papilla (MDP) size, common bile duct stones, sludge, Mirizzi syndrome, impacted stone in MDP. Significant differences were found in number of common bile duct stones: 1-2 stones (p<0,001) and multiple stones (p<0,05).

Conclusions. Risk factors for bacteriobilia is 1-2 stones in the common bile duct (p<0,001). Multiple stones (≥3) are not associated with bacteriobilia (p<0,05).

References

1. Salvador VB1, Lozada MC, Consunji RJ. Microbiology and antibiotic susceptibility of organisms in bile cultures from patients with and without cholangitis at an Asian academic medical center. Surg Infect (Larchmt). 2011 Apr;12(2):105-11. doi: 10.1089/sur.2010.005.
2. Csendes A, Burdiles P, Maluenda F, Diaz JC, Csendes P, Mitru N. Simultaneous Bacteriologic Assessment of Bile From Gallbladder and Common Bile Duct in Control Subjects and Patients With Gallstones and Common Duct Stones. Arch Surg. 1996 Apr; 131(4):389-94. DOI: 10.1001/archsurg.1996.01430160047008
3. Kiriyama S, Takada T, Hwang TL, Akazawa K, Miura F, Gomi H et al. Clinical application and verification of the TG13 diagnostic and severity grading criteria for acute cholangitis: an international multicenter observational study. J Hepatobiliary Pancreat Sci. 2017 Jun;24(6):329-337. doi: 10.1002/jhbp.458.
4. Sokal A, Sauvanet A, Fantin B, Lastours V. Acute cholangitis: Diagnosis and management. J Visc Surg. 2019 Dec;156(6):515-525. doi: 10.1016/j.jviscsurg.2019.05.007.
5. Об унификации микробиологических (бактериологических) методов исследования, применяемых в клинико-диагностических лабораториях лечебно-профилактических учреждений: приказ № 535. – М.: МОЗ СССР, 1985. – 65 с.
6. Lan Cheong Wah D, Christopher Christophi C, Muralidharan V. Acute cholangitis: current concepts. ANZ J Surg 2017. Jul;87(7-8):554-559. doi: 10.1111/ans.13981.
7. Takeshi Tsujinoa, Reimu Sugitaa, Haruhiko Yoshidaa, Hiroshi Yagiokaa, Hirofumi Kogurea, Takashi Sasakia, et al. Risk factors for acute suppurative cholangitis caused by bile duct stones. European Journal of Gastroenterology & Hepatology 2007, 19:585–588. DOI: 10.1097/MEG.0b013e3281532b78
8. Yeom DH, Oh HJ, Son YW, Kim TH. What Are the Risk Factors for Acute Suppurative Cholangitis Caused by Common Bile Duct Stones? Gut and Liver, Vol. 4, No. 3, September 2010: 363-367. DOI: 10.5009/gnl.2010.4.3.363
9. И. Н. Мамонтов, Т. И. Тамм, К. А. Крамаренко, С. Г. Белов, А. Я. Бардюк, А. П. Захарчук и др. Факторы риска развития и проявления острого холангита у больных с доброкачественной обструкцией внепеченочных желчных путей. Klinichna khirurhiia. 2019 September;86(9):32-37. DOI: 10.26779/2522-1396.2019.09.32
Published
2019-12-25
How to Cite
Mamontov, I. N. (2019). NUMBER OF COMMON BILE DUCT STONES WITHOUT CHOLANGITIS CORRELATES WITH BACTERIOLOGIC ASSESSMENT OF BILE. Kharkiv Surgical School, (5-6), 26-29. https://doi.org/10.37699/2308-7005.5-6.2019.05
Section
ORIGINAL RESEARCHES