• V. N. Lykhman
  • A. N. Shevchenko
  • A. O. Merkulov
  • D. A. Myroshnychenko
  • S. V. Tkach
  • E. O. Beloded
  • S. Yu. Bityak
  • A. V. Tokarev
Keywords: widespread purulent peritonitis, abdominal drainage, peritoneal dialysis.


Summary. Purpose. Study of the effectiveness of permanent transmembrane peritoneal dialysis in “semi-closed” management of the abdominal cavity (BP) in patients with advanced purulent peritonitis (APP).

Materials and methods. The results of treatment of 63 patients with APP with “semi-closed” administration in the abdominal cavity (BP) were analyzed. Depending on the features of BP drainage, patients with RGP were divided into two groups: comparison group (CG) — 31 patients who used traditional methods of abdominal drainage and the main group (MG) — 32 patients who underwent permanent peritoneal surgery in the postoperative period. dialysis through an artificial semipermeable membrane.

Results and discussion. A study of the relationship between the levels of molecules of average weight in spent dialysis solution with the severity of multiorgan failure (MF) on the SOFA scale using Spearman’s correlation analysis revealed an average degree of correlation: 1 day after surgery - r = 0.63 (p = 0.01), for 3 days — r = 0.75
(p = 0.001). The average degree of correlation between these indicators can be explained by the fact that in addition to endotoxicosis, the severity of MF in the next day after surgery also affects surgery. This is also confirmed by the increase in the correlation coefficient by 3 days, when the degree of influence of the operating aid on the severity of MF decreases.

The postoperative period was complicated in 14 (22.2 ± 5.2 %) patients with APP: in CG in 10 (32.3 ± 8.4 %) cases in MG - in 4 (12.5 ± 5.8 %) p = 0.059). Mortality of patients with APP at “semi-closed” management of an abdominal cavity made 19,0 ± 4,9 %: in MG — (25,8 ± 7,9) %, in MG — (12,5 ± 5,8) % (p = 0,179).

Conclusions. The proposed method of peritoneal dialysis reduced the absolute risk of postoperative complications in patients with advanced purulent peritonitis by 19.8 %.


1. Savchenko AA, Gvozdev II, Borisov AG, i dr. Osobennosti fagocitarnoj aktivnosti i sostojanija respiratornogo vzryva nejtrofilov krovi u bol’nyh rasprostranennym gnojnym peritonitom v dinamike posleoperacionnogo perioda. Infekcija i immunitet. 2017;1:51-60. [In Rus.]
2. Baoli C, Zhongwang L, Jingya W, et al. Comparison of the Performance Between Sepsis–1 and Sepsis–3 in ICU in China: A Retrospective Multicenter Study. Shock. 2017;3:301-6.
3. Jovenko IA, Balaka IV. Programma „AntimicrobialStewardship” – strategija antimikrobnogo kontrolja v OIT v jepohu antibiotikorezistentnosti. Gostrі ta nevіdkladnі stani u prakticі lіkarja. 2017;5-6:5-14. [In Rus.]
4. Zatevahin II. Abdominal’naja hirurgija M.: GJeOTAR- Media, 2017. 912 s.
5. Kaminskij IV, Kostyrnoj AV, Kosenko AV. Aspekty hirurgii posleoperacionnogo peritonita. Tavricheskij mediko-biologicheskij vestnik. 2016; 3:54-8. [In Rus.]
6. Dupont H, Guilbart M, Ntouba A, et al. Can yeast isolation be predicted in complicated secondary non–postoperative intra–abdominal infections. Critical Care. 2015;19:60.
7. Sartelli M, Catena F, Fikri M, et al. Management of intra-abdominal infections: recommendations by the World Society of Emergency Surgery. 2016 Consensus conference. World Journal of Emergency Surgery. 2017;12:22.
8. Xu JY, Chen QH, Liu SQ. The Effect of Early Goal–Directed Therapy on Outcome in Adult Severe Sepsis and Septic Shock Patients: A Meta– Analysis of Randomized Clinical Trials. Anesthesia and Analgesia. 2016;2:371-81.
9. Poljans’kij ІJu, Moroz PV, Moskaljuk VІ, ta іn. Lіkuvannja peritonіtu – shljah vіd dokazovoї do personalіzovanoї medicini. Harkіvs’ka hіrurgіchna shkola. 2017; 82:59-63. [In Ukr.]
How to Cite
Lykhman, V. N., Shevchenko, A. N., Merkulov, A. O., Myroshnychenko, D. A., Tkach, S. V., Beloded, E. O., Bityak, S. Y., & Tokarev, A. V. (2020). SANITATION OF THE ABDOMINAL CAVITY IN WIDESPREAD PERITONITIS. Kharkiv Surgical School, (4), 37-42.

Most read articles by the same author(s)