THE USE OF CYTOLOGICAL STUDIES TO DETERMINE THE READINESS OF BURN WOUNDS FOR AUTODERMOPLASTY
Summary. For an objective assessment of the readiness of burn wounds for autodermoplasty, a cytological technique was used, which allowed to improve the healing of skin flaps, the number of surgical interventions and the treatment time of patients were reduced.
Objective. To improve the results of skin grafting in connection with the use of an objective cytological method for studying the wound process, which allows you to determine the readiness of the wound bed for autodermoplasty.
Materials and methods. In 2019, 29 victims of the main group with deep burns, the cytological method of studying wound prints was used, the comparison group consisted of 32 patients with burns of the same depth and area in which indications for autodermoplasty were determined based on visual criteria.
The results of the study and their discussion. The goal of local preoperative treatment was to achieve an inflammatory-regenerative type of cytograms with a significant decrease in leukocytes, degenerative-destructive forms of neutrophils and the number of bacterial cells. At the same time, the number of polyblasts, macrophages and fibroblasts increased significantly, and there was also a tendency to increase the percentage of lymphocytes. In the main group, autodermoplasty operations were performed only when the indicated type of cytograms was achieved, which allowed to improve the percentage of engraftment of skin flaps, reduce the number of surgical interventions and the treatment time.
Conclusion. For the prognostic assessment of the readiness of deep burns for skin grafting, the cytological method of wound prints was applied. Determination of regenerative types of wound prints gives rise to autodermoplasty.
2. Saeidinia A., Keihanian F., Lashkari AP., Lahiji HG., Mobayyen M., Heidarzade A., Golchai J. Partial-thickness burn wounds healing by topical treatment: A randomized controlled comparison between silver sulfadiazine and centiderm. Medicine (Baltimore), 2017, Mar; 96(9): e6168, doi: 10.1097/MD.0000000000006168.
3. Datsenko, B. M. (2007). The wound process as a fundamental problem of modern clinical surgery. Bulletin of the Ukrainian Medical And Dental Academy, 7(1-2), 212-214. (in Russian).
4. Protsenko O.S., Shapoval O. V., Teslenko G. O., Rodіonov M.O. Metodi otsіnki perebіgu ranovogo protsesu. Aktual’nі problemi suchasnoї meditsini, 2019, no. 4, pp.3-11. (https://periodicals.karazin.ua/apmm/issue/view/937). (in Ukrainian).
5. Kravtsov O.V., Kozіn Yu.I., Іsaev Yu.І., Tsogoev A.A. Sposіb mіstsevogo lіkuvannya rozpovsyudzhennikh dermal’nikh opіkіv [Method of local treatment widespread dermal burns]. Patent no. 116950 u UA, A61V 17/00, 2017. (In Ukrainian).
6. Kravtsov O.V., Kozіn Yu.І., Іsaev Yu.І., Tsogoev A.A. Sposіb stimulyatsії prizhivlennya vіl’nikh autotransplantatіv pri glibokikh opіkakh [ A method of stimulation of engraftment free autografts in deep burns] Patent no. 118139 u UA, A61F 13/00, 2017. (In Ukrainian).
7. Kravtsov O.V, Boyko V.V., Kozіn Yu.І. Sposіb nekrotomії pri opіkovikh Urazhennyakh [Method of necrotomy in burns lesions]. Patent no. 95223 u UA, A61B 17/00, 2014. (In Ukrainian).
8. Pokrovskaya, M.P., Makarov, M.S. (1942) Cytology of wound exudate as an indicator of the wound healing process. Moscow: Medgiz. (in Russian).
9. Kamaev, M. F. (1962). The infected wound and its treatment. Moscow: Medicine. (in Russian)
10. Datsenko, B. M. (2007). The wound process as a fundamental problem of modern clinical surgery. Bulletin of the Ukrainian Medical And Dental Academy, 7(1-2), 212-214. (in Russian)